Author

V. D. Dedeepiya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

N. Ikewaki· 3 shared R. Senthilkumar· 3 shared S. J. Abraham· 3 shared S. Preethy· 3 shared G. A. Levy· 2 shared G. Kurosawa· 2 shared M. Iwasaki· 2 shared S. Vaddi· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersPharmacology & Toxicology

N. Ikewaki

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Two unique biological response-modifier glucans beneficially regulating gut microbiota and faecal metabolome in a non-alcoholic steatohepatitis animal model, with potential for applications in human health and disease

S. Preethy, N. Ikewaki, G. A. Levy, K. Raghavan, V. D. Dedeepiya, N. Yamamoto, S. Srinivasan, N. Ranganathan, M. Iwasaki, R. Senthilkumar, S. J. Abraham

This study evaluates the effects of two glucans on gut microbiota and metabolome in a NASH model, showing beneficial changes in microbial composition and metabolite levels.

BMJ Open Gastroenterology · Sep 1, 2022Peer-reviewedMicrobiology

Beneficial effects of novel strains of Aureobasidium pullulans produced 1,3-1,6 β-glucans on non-esterified fatty acid levels in diabetic KKAy mice

N. Ikewaki, T. Onaka, Y. Ikeue, M. Nagataki, G. Kurosawa, V. D. Dedeepiya, M. Rajmohan, S. Vaddi, R. Senthilkumar, S. Preethy, S. J. Abraham

This study compares two Aureobasidium pullulans strains producing beta-glucans in reducing non-esterified fatty acids in diabetic KK-Ay mice, finding N-163 significantly lowers NEFA levels.

bioRxiv · Jul 22, 2021 · PreprintPharmacology & Toxicology

Hepatoprotective effects of Aureobasidium pullulans derived Beta 1,3-1,6 biological response modifier glucans in a STAM- animal model of non-alcoholic steatohepatitis

N. Ikewaki, G. Kurosawa, M. Iwasaki, S. Preethy, V. D. Dedeepiya, S. Vaddi, R. Senthilkumar, G. A. Levy, S. J. Abraham

This study evaluates the hepatoprotective effects of two Aureobasidium pullulans beta glucans in a NASH mouse model, showing reduced inflammation and fibrosis.

bioRxiv · Jul 8, 2021 · PreprintPharmacology & Toxicology