Author

V. DiGiacomo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Beeler· 1 shared A. I. de Opakua· 1 shared A. Luebbers· 1 shared F. J. Blanco· 1 shared J. Zhao· 1 shared J.-C. Park· 1 shared M. Ferreras-Gutierrez· 1 shared M. Garcia-Marcos· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Beeler

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Author profile →

1 paper

Recent·Most cited

Small-molecule targeting of GPCR-independent non-canonical G protein signaling inhibits cancer progression

J. Zhao, V. DiGiacomo, M. Ferreras-Gutierrez, S. Dastjerdi, A. I. de Opakua, J.-C. Park, A. Luebbers, Q. Chen, A. Beeler, F. J. Blanco, M. Garcia-Marcos

This study introduces IGGi-11, a small-molecule inhibitor that blocks non-canonical G-protein signaling by disrupting GIV/Girdin interaction, inhibiting cancer metastasis without affecting canonical GPCR signaling.

bioRxiv · Feb 18, 2023Biochemistry