Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation
A. D. Stephens, P. Z. Liu, V. Kandula, H. Chen, L. M. Almassalha, V. Backman, T. O'Halloran, S. A. Adam, R. D. Goldman, E. J. Banigan, J. F. Marko
This study shows that extracellular cations alter nuclear shape and mechanics through heterochromatin formation, rescuing nuclear morphology in disease models.
bioRxiv · Sep 21, 2018Cell Biology