Author

V. L. S. LaPointe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Schumacher· 2 shared F. A. A. Ruiter· 2 shared F. L. C. Morgan· 2 shared M. B. Baker· 2 shared C. W. van den Berg· 1 shared G. G. Slaats· 1 shared L. E. Wiersma· 1 shared L. Moroni· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

A. Schumacher

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Author profile →

2 papers

Recent·Most cited

Soft, dynamic hydrogel confinement improves kidney organoid lumen morphology and reduces epithelial-mesenchymal transition in culture

F. A. A. Ruiter, F. L. C. Morgan, N. Roumans, A. Schumacher, G. G. Slaats, L. Moroni, V. L. S. LaPointe, M. B. Baker

This study shows that soft, dynamic hydrogels improve kidney organoid morphology and reduce epithelial-mesenchymal transition compared to stiff hydrogels.

bioRxiv · Nov 10, 2021Bioengineering

Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

T. Geuens, F. A. A. Ruiter, A. Schumacher, F. L. C. Morgan, T. Rademakers, L. E. Wiersma, C. W. van den Berg, T. J. Rabelink, M. B. Baker, V. L. S. LaPointe

This study shows that encapsulating kidney organoids in a thiol-ene cross-linked alginate hydrogel reduces abnormal type 1a1 collagen deposition, improving their extracellular matrix composition and bringing them closer to clinical application.

bioRxiv · Nov 17, 2020Bioengineering