The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in the Enterobacterales
A. J. Cartagena, K. L. Taylor, L. C. Lopez, J. Su, J. T. Smith, A. L. Manson, J. D. Chen, V. M. Pierce, A. M. Earl, R. P. Bhattacharyya
This study shows that carbapenemase-producing CRE exhibit an inoculum effect, which can mislead susceptibility testing and highlights the need for improved detection methods.
bioRxiv · May 23, 2023 · PreprintMicrobiology