CELL CYCLE ASYNCHRONY GENERATES DNA DAMAGE AT MITOTIC ENTRY IN POLYPLOID CELLS
M. Nano, A. Simon, C. Pennetier, V. Fraisier, V. Marthiens, R. Basto
This study shows that polyploid cells generate DNA damage at mitotic entry due to cell cycle asynchrony, contributing to genetic instability in Drosophila and mouse neural stem cells.
bioRxiv · Mar 20, 2019Cell Biology