Author

V. R. Chirasani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:graph neural network· 1

Frequent Co-Authors

C. M. Furdui· 1 shared D. Parsonage· 1 shared G. A. Hobbs· 1 shared G. Meissner· 1 shared H. Wu· 1 shared J. Lee· 1 shared K. I. Popov· 1 shared L. B. Poole· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

C. M. Furdui

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2 papers

Recent·Most cited

Kinetic and Redox Characterization of KRAS G12C Inhibition

M. V. Huynh, D. Parsonage, T. E. Forshaw, V. R. Chirasani, G. A. Hobbs, H. Wu, J. Lee, C. M. Furdui, L. B. Poole, S. L. Campbell

This study characterizes the kinetic and redox properties of KRASG12C inhibition, revealing pH-dependent covalent ligation and oxidation effects on protein conformation.

bioRxiv · Apr 3, 2022Biochemistry

Mapping Co-regulation Pathways among Ligand Binding sites in RyR1

V. R. Chirasani, K. I. Popov, G. Meissner, N. V. Dokholyan

The paper maps co-regulation pathways among ligand binding sites in RyR1 using a graph-theoretical approach to understand how Ca2+, ATP, and caffeine synergistically regulate the channel.

bioRxiv · Jun 19, 2019 · PreprintBiophysics