Exacerbation of mitochondrial fission in human CD34+ cells halts erythropoiesis and hemoglobin biosynthesis
A. M. Gonzalez, L. M. Ruiz, E. L. Jensen, C. A. Echeverria, V. Romero, L. Stiles, O. S. Shirihai, A. A. Elorza
This study shows that excessive mitochondrial fission in human CD34+ cells disrupts erythropoiesis and hemoglobin biosynthesis by altering mitochondrial morphology and function.
bioRxiv · Jul 31, 2020 · PreprintCell Biology