Author

V. Roukos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Assay:Hi-C· 1

Frequent Co-Authors

N. Crosetto· 2 shared A. Mizi· 1 shared A. Papantonis· 1 shared A. Sapino· 1 shared B. A. M. Bouwman· 1 shared B. Han· 1 shared C. Diekmann· 1 shared C. F. Nielsen· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

N. Crosetto

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Author profile →

2 papers

Recent·Most cited

High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue

N. Zhang, L. Harbers, M. Simonetti, C. Diekmann, Q. Verron, E. Berrino, S. E. Bellomo, G. M. C. Longo, M. Ratz, N. Schultz, F. Tarish, P. Su, B. Han, W. Wang, S. Onorato, , N. Crosetto

bioRxiv · Nov 7, 2023Cancer Biology

Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations

H. J. Gothe, B. A. M. Bouwman, E. G. Gusmao, R. Piccinno, S. Sayols, O. Drechsel, G. Petrosino, V. Minneker, N. Josipovic, A. Mizi, C. F. Nielsen, E.-M. Wagner, S. Takeda, H. Sasanuma, D. F. Hudson, , V. Roukos

The paper shows that transcription and spatial chromosome folding increase DNA fragility, leading to oncogenic translocations in leukemia.

bioRxiv · Dec 3, 2018Cell Biology