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7 papers
Recent·Most cited
Y. Zabrodskaya, V. B. Tsvetkov, A.-P. Shurygina, K. Vasyliev, A. Shaldzhyan, A. N. Gorshkov, A. Kuklin, N. Fedorova, V. V. Egorov
The paper investigates how an influenza NS1 peptide interacts with TCR intramembrane domains to suppress immune responses using structural and biophysical methods.
bioRxiv · Dec 25, 2023Biophysics
V. V. Egorov, A. V. Shvetsov, E. B. Pichkur, A. A. Shaldzhyan, Y. A. Zabrodskaya, D. S. Vinogradova, P. A. Nekrasov, A. N. Gorshkov, Y. P. Garmay, A. A. Kovaleva, L. A. Stepanova, L. M. Tsybalova, T. A. Shtam, A. G. Myasnikov, A. L. Konevega
The paper studies the structure of HBc and HBc/4M2e particles using cryo-EM and molecular modeling, showing amyloid-like fibril formation of M2e fragments and a high-resolution model of HBc-4M2e.
bioRxiv · Jul 4, 2022Biophysics
L. A. Ivanova, D. A. Golovkina, E. V. Zhurishkina, Y. P. Garmay, A. Y. Baranchikov, N. V. Tsvigun, Y. A. Zabrodskaya, A. D. Yapryntsev, A. N. Gorshkov, K. I. Lebedev, A. A. Shaldzhyan, G. P. Kopitsa, V. V. Egorov, A. A. Kulminskaya
This study investigates how Bacillus licheniformis planktonic cells induce CaCO3 biomineralization through extracellular matrix formation and crystal growth pathways.
bioRxiv · Oct 22, 2020 · PreprintMicrobiology
O. I. Antimonova, N. A. Grudinina, V. V. Egorov, V. V. Ilyin, Y. A. Zabrodskaya, E. S. Ramsay, V. A. Polukeev, M. M. Shavlovsky
The paper synthesizes a dye similar to fluorene and Congo red, showing it changes fluorescent spectrum when interacting with amyloid-like fibrils of proteins like lysozyme and insulin.
bioRxiv · Jun 10, 2019Biochemistry
O. I. Antimonova, D. V. Lebedev, Y. A. Zabrodskaya, N. A. Grudinina, M. M. Shavlovsky, V. V. Egorov
The paper compares the fluorescence lifetime of SF and SF-IAPP in polyacrylamide gel, showing differences in monomer and fibril states and suggests FLIM for studying amyloidogenic proteins.
bioRxiv · May 9, 2018Biophysics
Y. A. Zabrodskaya, A. V. Shvetsov, V. B. Tsvetkov, V. V. Egorov
The paper investigates how triazavirine forms supramolecular complexes with melittin, leading to aggregation, using molecular dynamics and docking simulations.
bioRxiv · Apr 21, 2018Biophysics
Y. A. Zabrodskaya, D. V. Lebedev, M. A. Egorova, A. A. Shaldzhyan, A. V. Shvetsov, A. I. Kuklin, D. S. Vinogradova, N. V. Klopov, O. V. Matusevich, T. A. Cheremnykh, R. Dattani, V. V. Egorov
This paper investigates the amyloidogenic properties of the PB1-derived peptide and links its antiviral activity to conformational changes in the influenza virus polymerase complex.
bioRxiv · Oct 31, 2017Biophysics