V. V. Nazarenko

The study identifies EsLuxA from Enhygromyxa salina as a functional homodimeric luciferase that produces light in vitro and in vivo, suggesting a simplified evolutionary pathway for bioluminescence.

The paper develops twenty-two finely tuned flavin-binding fluorescent proteins for multicolor imaging by modifying the chromophore's spectral properties.

The paper investigates how mutations of Gln148 in LOV domains affect their absorption spectra and structure, revealing blue shifts and pH sensitivity in certain variants.

The paper identifies structural and mechanistic causes of spectral tuning in flavin-binding fluorescent proteins through mutagenesis, X-ray crystallography, and computational methods, enabling two-color microscopy.