Author

G. A. Lomberk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2

Frequent Co-Authors

R. A. Urrutia· 4 shared J. L. Iovanna· 3 shared O. Gayet· 2 shared A. Carrier· 1 shared A. El kaoutari· 1 shared A. Gonzalez· 1 shared A. Mathison· 1 shared A. Salmonson· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCancer Biology

R. A. Urrutia

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

EHMT2 Inactivation in Pancreatic Epithelial Cells Shapes the Transcriptional Landscape and Inflammation Response of the Whole Pancreas

G. Pollin, A. Mathison, T. Milech de Assuncao, A. Thomas, L. Zeighami, A. Salmonson, H. Liu, G. Urrutia, P. Vankayala, S. J. Pandol, M. T. Zimmermann, J. L. Iovanna, V. X. Jin, R. A. Urrutia, G. A. Lomberk

bioRxiv · Mar 14, 2024Cancer Biology

A GATA6-centered gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer

P. Martinelli, B. Kloesch, N. Hruschka, V. Ionasz, R. Oellinger, S. Mueller, J. Martinez de Villareal, H. P. Dienes, M. Schindl, E. Gruber, J. Stift, G. A. Lomberk, B. Seidler, D. Saur, R. Rad, , F. X. Real

This paper identifies a GATA6-centered gene regulatory network involving HNFs and ΔNp63 that controls plasticity and immune escape in pancreatic cancer, showing GATA6 loss is necessary but not sufficient for the basal phenotype.

Gut · Apr 12, 2021Peer-reviewedCancer Biology

Metabolomic profiling of pancreatic adenocarcinoma reveals fundamental clinical features

J. L. IOVANNA, A. El kaoutari, N. Fraunhoffer, O. Hoare, C. Teyssedou, O. Gayet, J. Roques, G. A. Lomberk, R. A. Urrutia, N. J. Dusetti

This study identifies a metabolic signature in pancreatic adenocarcinoma that predicts clinical outcomes and drug resistance, suggesting metabolic targeting as a therapeutic strategy.

bioRxiv · Feb 1, 2021Cancer Biology

Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis

J. L. Iovanna, P. Santofimia-Castano, W. Lan, J. Bintz, O. Gayet, A. Carrier, G. A. Lomberk, J. l. Neira, A. Gonzalez, R. A. Urrutia, P. Soubeyran

This paper shows that inactivating NUPR1 in pancreatic cancer cells causes ER stress, mitochondrial dysfunction, and necrotic cell death independent of caspases.

bioRxiv · Mar 6, 2018Cell Biology