Author

Valentine Duclos

Institut universitaire de cardiologie et de pneumologie de Québec

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Anne Rufiange· 3 shared Mewen BriendiD· 3 shared Patrick MathieuiD· 3 shared Yohan BosséiD· 3 shared Louis-Hippolyte Minvielle MonclaiD· 2 shared Samuel MathieuiD· 2 shared Sébastien ThériaultiD· 2 shared Benoît J. ArsenaultiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Anne Rufiange

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3 papers

Recent·Most cited

Decoding causal genes and programs from regulatory variants in aortic valve disease

Mewen Briend, Anne Rufiange, Valentine Duclos, Samuel Mathieu, Thibault Kanmacher, Dominique K. Boudreau, Nathalie Gaudreault, Victoria E. S. Armero, François Dagenais, Christian Couture, Philippe Joubert, Sébastien Thériault, Yohan Bossé, Patrick Mathieu

The paper identifies regulatory variants associated with aortic valve disease and shows their impact on gene expression and disease mechanisms.

bioRxiv · May 29, 2026 · PreprintGenetics

Efficient molecular mendelian randomization screens with LaScaMolMR.jl

Samuel Mathieu, Louis-Hippolyte Minvielle Moncla, Mewen Briend, Valentine Duclos, Anne Rufiange, Yohan Bossé, Patrick Mathieu

LaScaMolMR.jl enables efficient large-scale molecular Mendelian randomization studies by providing a fast, integrated Julia package for omic-wide MR analyses.

medRxiv · Aug 29, 2024 · PreprintGenetic & Genomic Medicine

Integrative Analysis of the Blood Proteome by Mendelian Randomization Reveals Regulatory Networks in Calcific Aortic Valve Disease

Mewen Briend, Louis-Hippolyte Minvielle Moncla, Valentine Duclos, Samuel Mathieu, Anne Rufiange, Sébastien Thériault, Benoît J. Arsenault, Yohan Bossé, Patrick Mathieu

This paper uses Mendelian randomization to identify 49 blood proteins causally associated with calcific aortic valve disease, revealing immune and growth factor pathways involved in the disease.

medRxiv · Jul 26, 2023 · PreprintGenetic & Genomic Medicine