Author

Dominique K. Boudreau

Institut universitaire de cardiologie et de pneumologie de QuébecORCID 0000-0002-2406-2447Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Yohan BosséiD· 3 shared Nathalie GaudreaultiD· 2 shared Patrick MathieuiD· 2 shared Philippe JoubertiD· 2 shared Sébastien RenautiD· 2 shared Sébastien ThériaultiD· 2 shared Victoria E. S. ArmeroiD· 2 shared Alexandra Jochmans‐LemoineiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersGenetics

Yohan BosséORCID

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3 papers

Recent·Most cited

Decoding causal genes and programs from regulatory variants in aortic valve disease

Mewen Briend, Anne Rufiange, Valentine Duclos, Samuel Mathieu, Thibault Kanmacher, Dominique K. Boudreau, Nathalie Gaudreault, Victoria E. S. Armero, François Dagenais, Christian Couture, Philippe Joubert, Sébastien Thériault, Yohan Bossé, Patrick Mathieu

The paper identifies regulatory variants associated with aortic valve disease and shows their impact on gene expression and disease mechanisms.

bioRxiv · May 29, 2026 · PreprintGenetics

Cell-Specific Transcriptomic and Mito-Nuclear Imbalance in Lungs Under Intermittent Hypoxia in Adult Male Mice.

Alexandra Jochmans‐Lemoine, François Marcouillier, Marie Martelat, Ynuk Bossé, Dominique K. Boudreau, Sébastien Renaut, Yohan Bossé, Vincent Joseph

This study examines real-time transcriptional responses to intermittent hypoxia in lung tissue of male mice, revealing cell-type-specific changes and mito-nuclear imbalance.

bioRxiv · Aug 5, 2025 · PreprintPhysiology

Single-cell and single-nucleus RNA-sequencing from paired normal-adenocarcinoma lung samples provide both common and discordant biological insights

Sébastien Renaut, Victoria E. S. Armero, Dominique K. Boudreau, Nathalie Gaudreault, Patrice Desmeules, Sébastien Thériault, Patrick Mathieu, Philippe Joubert, Yohan Bossé

This study compares scRNA-seq and snRNA-seq in lung samples, finding differences in cell type composition and biological insights between fresh and frozen tissues.

PLoS Genetics · May 30, 2024Peer-reviewedCancer Biology