The PPE2 protein of Mycobacterium tuberculosis is responsible for the development of hyperglycemia and insulin resistance during tuberculosis
Manoj Kumar Bisht, Vandana Maurya, Priyanka Dahiya, Vijaya Lakshmi Valluri, Sudip Ghosh, Sangita Mukhopadhyay
This study identifies PPE2 as a Mycobacterium tuberculosis protein that induces insulin resistance and hyperglycemia by altering adipose tissue function and metabolism.
bioRxiv · Aug 13, 2025 · PreprintMicrobiology