Author

Manoj Kumar Bisht

Centre for DNA Fingerprinting and DiagnosticsORCID 0000-0002-3420-1754Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Priyanka DahiyaiD· 2 shared Sangita MukhopadhyayiD· 2 shared Sudip GhoshiD· 2 shared Aakash ChandramouliiD· 1 shared Abhishek Saha· 1 shared Siddhesh S. KamatiD· 1 shared Vandana Maurya· 1 shared Vijaya Lakshmi ValluriiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

Priyanka DahiyaORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 13, 2025

The PPE2 protein of Mycobacterium tuberculosis is responsible for the development of hyperglycemia and insulin resistance during tuberculosis

Manoj Kumar Bisht, Vandana Maurya, Priyanka Dahiya…·Sangita Mukhopadhyay

This study identifies PPE2 as a Mycobacterium tuberculosis protein that induces insulin resistance and hyperglycemia by altering adipose tissue function and metabolism.

DOI 10.1101/2025.08.13.670014

mouseexperimental assay

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MicrobiologybioRxivPreprintJul 31, 2025

PE11 promotes intracellular persistence of Mycobacterium tuberculosis by inhibiting autophagy and lysosomal biogenesis by targeting the FLCN-lactate-TFEB signaling axis

Priyanka Dahiya, Manoj Kumar Bisht, Abhishek Saha…·Sangita Mukhopadhyay

This study identifies PE11 as a factor that promotes Mtb persistence by inhibiting autophagy and lysosomal biogenesis through the FLCN-lactate-TFEB signaling axis, with lactate shown to enhance bacterial clearance.

1 citation

experimental assaygenetic perturbation / CRISPR

𝕏 PostBluesky