Sudip Ghosh

This study identifies distinct plasma metabolite profiles in COPD patients based on smoking status using GC-MS, finding 23 and 36 altered metabolites in smokers and ex-smokers, respectively, and five diagnostic metabolites with AUC > 0.8.

This study identifies PPE2 as a Mycobacterium tuberculosis protein that induces insulin resistance and hyperglycemia by altering adipose tissue function and metabolism.

This study identifies PE11 as a factor that promotes Mtb persistence by inhibiting autophagy and lysosomal biogenesis through the FLCN-lactate-TFEB signaling axis, with lactate shown to enhance bacterial clearance.

This study characterizes the structure and function of PE11 esterase from Mycobacterium tuberculosis, showing its role in virulence and potential as a therapeutic target.