Author

Vanessa Gumz

Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ana Fernández‐VillegasiD· 1 shared Anushree Kelkar· 1 shared Christian GallreiniD· 1 shared Franziska Hirsch· 1 shared Gabriele S. Kaminski SchierleiD· 1 shared Gurleen Kaur KalsiiD· 1 shared Janine KirsteiniD· 1 shared Mira Sleiman· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Ana Fernández‐VillegasORCID

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1 paper

Recent·Most cited

Impairment of neuronal activity occurs at the early stages of the aggregation cascade of Ab1-42 and mutant Tau

Franziska Hirsch, Nino F. Läubli, Anushree Kelkar, Mira Sleiman, Yvonne Woitzat, Christian Gallrein, Vanessa Gumz, Gurleen Kaur Kalsi, Ana Fernández‐Villegas, Gabriele S. Kaminski Schierle, Janine Kirstein

The paper shows that Aβ and mutant Tau reduce neuronal activity in young C. elegans before amyloid aggregation, with muscle-expressed Aβ affecting neurons via retrograde signaling.

Disease Models & Mechanisms · Feb 23, 2026Peer-reviewedNeuroscience