Glycyl-tRNA sequestration is a unifying mechanism underlying GARS1-associated peripheral neuropathy
Natalia Mora, Erik F. J. Slot, Vanessa Lewandowski, Maria P. Menafra, Moushami Mallik, Pascal van Lith, Céline Sijlmans, Nick H. M. van Bakel, Zoya Ignatova, Erik Storkebaum
The paper identifies tRNAGly sequestration as a unifying mechanism causing GARS1-associated peripheral neuropathy and suggests therapeutic strategies to elevate tRNAGly levels.
Nucleic Acids Research · Mar 3, 2025Peer-reviewedNeuroscience