Nick H. M. van Bakel

Glycyl-tRNA sequestration is a unifying mechanism underlying GARS1-associated peripheral neuropathy

The paper identifies tRNAGly sequestration as a unifying mechanism causing GARS1-associated peripheral neuropathy and suggests therapeutic strategies to elevate tRNAGly levels.

Loss of nucleoporin Nup50 is a risk factor for amyotrophic lateral sclerosis

The paper identifies NUP50 gene variants and reduced expression as risk factors for ALS through transcriptome-wide association and functional studies.

Action of cocaine involves depletion of dopaminergic and serotonergic storage vesicles

This study shows cocaine increases extracellular dopamine and serotonin by depleting storage vesicles in the rat nucleus accumbens, with individual differences in vesicular release affecting behavior and drug intake.