ONC206 demonstrates potent anti-tumorigenic activity and is a potential novel therapeutic strategy for high-risk medulloblastoma
Theophilos Tzaridis, Jingbo Liu, Franklin Chien, Anshu Malhotra, Dan Zhu, Isabella Gershon, Hongying Zhang, José E. Velázquez Vega, Matthew Schniederjan, Teresa Sposito, Peter D. Adams, Joshua E Allen, Varun V. Prabhu, Robert J. Wechsler‐Reya, T. MacDonald
This study shows ONC206 effectively kills medulloblastoma cells and extends survival in mouse models, supporting its potential as a new treatment for high-risk medulloblastoma.
Neuro-Oncology · Mar 6, 2026Peer-reviewedCancer Biology