Species-specific Rates of Fatty Acid MetabolismSet the Scale of Temporal Patterning of Corticogenesisthrough Protein Acetylation Dynamics
Ryohei Iwata, Isabel M. Gallego López, Emir Erkol, Ridha Limame, Anke Vandekeere, Nathan Bénac, Benita Turner-Bridger, Mélanie Planque, Martyna Ditkowska, Vera Lein, Franck Maurinot, Nicolas Peredo, Jochen Lamote, Antonela Bonafina, Pieter Vermeersch, , Pierre Vanderhaeghen
This study shows that species-specific fatty acid oxidation rates influence temporal patterning of corticogenesis through protein acetylation dynamics in human and mouse cortical progenitors.
bioRxiv · Aug 27, 2025 · PreprintNeuroscience