Emir Erkol

This study shows that species-specific fatty acid oxidation rates influence temporal patterning of corticogenesis through protein acetylation dynamics in human and mouse cortical progenitors.

This study shows ASPM mutations disrupt mitotic spindle orientation in human cortical progenitors, leading to premature oRGC generation and reduced cortical progenitor numbers.

This study shows that slower mitochondrial development and lower metabolic activity in human cortical neurons compared to mice delay neuronal maturation, and stimulating mitochondria accelerates this process.

This study identifies CROCCP2 as a human-specific gene that enhances cortical progenitor expansion by modulating cilia dynamics and mTOR signalling.