Vera M. DesMarais

Morphometric Analysis of the Thymic Epithelial Cell (TEC) Network Using Integrated and Orthogonal Digital Pathology Approaches

This paper introduces a digital pathology pipeline to analyze thymic structure and function, demonstrating its application in a mouse model of age-related thymic involution.

Intratumoral CXCL12 Gradients Contextualize Tumor Cell Invasion, Migration and Immune Suppression in Breast Cancer

This study shows CXCL12 gradients around TMEM doorways promote tumor cell invasion and create immunosuppressive niches by affecting CD8+ T cell function and distribution.

Unlocking the Potential: FKK6 as a Microbial Mimicry Based Therapy for Chronic Inflammation-Associated Colorectal Cancer in a Murine Model

This study evaluates FKK6, a microbial mimic of an indole metabolite, as a therapy for colitis-associated colorectal cancer in mice, showing anti-tumor effects and safety.