Author

Sakshi Goel

Albert Einstein College of MedicineORCID 0000-0002-5283-9049Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Sakshi Goel1 paper · Birla Institute of Technology and Science, Pilani

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Lindsay M. LaFaveiD· 2 shared Aaron Scott MansfieldiD· 1 shared Abigail Kazakov· 1 shared Adam L. MacLeaniD· 1 shared Agathe QuesneliD· 1 shared Aliona ZintiridouiD· 1 shared Allison S. HarneyiD· 1 shared Andrea Briceno· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Lindsay M. LaFaveORCID

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2 papers

Recent·Most cited

Senescent fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity

Jin Young Lee, Nabora S. Reyes, Sang‐Ho Woo, Nancy C. Allen, Tsukasa Kadota, Andrew J. Lechner, Ritusree Biswas, Sakshi Goel, Fia Stratton, Chaoyuan Kuang, Tatsuya Tsukui, Vincent C. Auyeung, Aaron Scott Mansfield, Lindsay M. LaFave, Tien Peng

This study identifies senescent fibroblasts in lung cancer stroma that alter tumor metabolism and plasticity, and shows that targeting these cells with XL888 reduces tumor burden.

Cell stem cell · Nov 3, 2025Peer-reviewedCancer Biology

Intratumoral CXCL12 Gradients Contextualize Tumor Cell Invasion, Migration and Immune Suppression in Breast Cancer

Dimitra P. Anastasiadou, Nicole Couturier, Sakshi Goel, Dimitrios G Argyris, Stepan Vodopyanov, Luis Rivera Sanchez, Edgar Gonzalez, Jesse Kreger, Anthony J. Griffen, Abigail Kazakov, Joseph Burt, Natasha Recoder, Camille L. Duran, Allison S. Harney, Agathe Quesnel, , George S. Karagiannis

This study shows CXCL12 gradients around TMEM doorways promote tumor cell invasion and create immunosuppressive niches by affecting CD8+ T cell function and distribution.

bioRxiv · Oct 15, 2024 · PreprintCancer Biology