Author

Leslie Gunther-Cummins

Albert Einstein College of MedicineORCID 0000-0002-9652-5578Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Frank MacalusoiD· 2 shared B. Tom BurnleyiD· 1 shared Cheri M. HamptoniD· 1 shared Chyongere Hsieh· 1 shared Colin M. PalmeriD· 1 shared David A. LewisiD· 1 shared Delfina LarreaiD· 1 shared Diane L. CarlisleiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Frank MacalusoORCID

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2 papers

Recent·Most cited

Uncovering synaptic and cellular nanoarchitecture of brain tissue via seamless in situ trimming and milling for cryo-electron tomography

Jiying Ning, Jill R. Glausier, Rangana Warshamanage, Leslie Gunther-Cummins, B. Tom Burnley, Colin M. Palmer, Guillermo González‐Burgos, Takeaki Miyamae, Jing Wang, Diane L. Carlisle, Chyongere Hsieh, Thomas Schmelzer, Silas A. Buck, Jonathan M. Franks, Cheri M. Hampton, , Zachary Freyberg

This paper introduces SISTM to map 3D synaptic nanoarchitecture in brain tissue across species using cryo-ET and STA, revealing conserved structural features in human postmortem tissue.

bioRxiv · Mar 9, 2025 · PreprintCell Biology

Alzheimer's-associated upregulation of mitochondria-associated ER membranes after traumatic brain injury

Rishi R. Agrawal, Delfina Larrea, Yimeng Xu, Lingyan Shi, Hylde Zirpoli, Leslie Gunther-Cummins, Valentina Emmanuele, Donghui Song, Taekyung D. Yun, Frank Macaluso, Wei Min, Steven G. Kernie, Richard Joseph Deckelbaum, Estela Área-Gómez

The paper investigates how traumatic brain injury (TBI) increases mitochondria-associated ER membranes (MAMs) and C99 levels, linking these changes to Alzheimer's disease (AD) through lipid metabolism alterations.

Cellular and Molecular Neurobiology · Dec 26, 2022Peer-reviewedNeuroscience