Hillary M. Guzik

This paper introduces a digital pathology pipeline to analyze thymic structure and function, demonstrating its application in a mouse model of age-related thymic involution.

This study shows CXCL12 gradients around TMEM doorways promote tumor cell invasion and create immunosuppressive niches by affecting CD8+ T cell function and distribution.

This study evaluates FKK6, a microbial mimic of an indole metabolite, as a therapy for colitis-associated colorectal cancer in mice, showing anti-tumor effects and safety.

This study identifies TMEM106B as an insoluble protein increased in MS plaques and shows its deletion causes axonal damage and lipid accumulation in demyelination models.