Neuronal and vascular genome-maintenance states organize opposing multicellular architectures in the aging brain
Arvin Koshboresh, Vijay Laxmi Roy, Mofida Abdelmageed, Steffy B. Manjila, Deniz Parmaksiz, Yongsoo Kim, Jesse A Gillis, Anirban Paul
The paper maps DNA damage response states in aging mouse brains, revealing opposing neuronal and vascular spatial patterns linked to genome maintenance.
bioRxiv · Oct 14, 2026 · PreprintNeuroscience