A single-dose recombinant rVSVΔG-CCHFV-GPC vaccine protects nonhuman primates against heterologous Crimean-Congo hemorrhagic fever virus challenge
Robert W. Cross, Kevin Melody, Rachel L O'Toole, Viktoriya Borisevich, Daniel J. Deer, Joan B. Geisbert, Courtney B. Woolsey, Krystle N. Agans, Abhishek N. Prasad, Dafna Abelson, Xhevat R. Jakupi, Lindita Ajazaj Berisha, Salih Ahmeti, Thomas W. Geisbert
This study shows a single dose of a recombinant rVSV vaccine protects nonhuman primates from CCHFV infection, with immune responses similar to human survivors.
bioRxiv · Oct 22, 2026 · PreprintMicrobiology