Thomas W. Geisbert

This study identifies key glycoprotein residues that enhance the efficacy of a CCHFV vaccine by modulating cleavage and fusogenicity in animal models.

This study shows a single dose of a recombinant rVSV vaccine protects nonhuman primates from CCHFV infection, with immune responses similar to human survivors.

This study infects nonhuman primates with Bundibugyo virus to examine disease progression and identify immune targets and inflammatory responses.

This study shows that 4-fluorouridine provides complete protection against lethal Nipah virus infection in hamsters when administered postexposure.

A single dose of ChAd3-SUDV vaccine protected macaques from lethal SUDV challenge via parenteral and aerosol routes.