Extracellular Vesicles Mediate Activation and Trafficking of Splenic Immune Cells to the Heart Post-Myocardial Infarction
Kaneez Fatima, Austin Angelotti, Vinay S. Kumar, Vishnu Chollangi, Wafa Aziz, Siddarth Dasari, Emily N Bianchini, Joseph Che‐Yen Wang, Suman Asalla, Harpreet Singh, Sumanth D. Prabhu, Shyam Sunder Bansal
This study shows that extracellular vesicles from the heart after myocardial infarction drive immune cell trafficking to the heart, and inhibiting these vesicles reduces inflammation and improves cardiac function.
bioRxiv · Jun 30, 2026 · PreprintImmunology