Author

Vruti Patel

University College London

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew W. StokeriD· 1 shared Christina KarapouliouiD· 1 shared Elliott M. Thompson· 1 shared Pedro R. CutillasiD· 1 shared Vinothini RajeeveiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

Andrew W. StokerORCID

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1 paper

Recent·Most cited

DUSP6 is transcriptionally upregulated by activated ALK and cooperates with ALK signaling to reduce lorlatinib sensitivity in neuroblastoma cells

Elliott M. Thompson, Vruti Patel, Christina Karapouliou, Vinothini Rajeeve, Pedro R. Cutillas, Andrew W. Stoker

This study identifies DUSP6 as a novel effector of ALK signaling in neuroblastoma, showing it enhances ALK-driven proliferation and reduces sensitivity to ALK inhibitors.

bioRxiv · Jun 11, 2026 · PreprintCancer Biology