Author

W. E. Lutz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

G. E. Borgstahl· 2 shared G. E. O. Borgstahl· 2 shared J. Azadmanesh· 2 shared K. L. Weiss· 2 shared L. Coates· 2 shared L. Struble· 2 shared M. J. Broadhurst· 2 shared S. Khurana· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiochemistry

G. E. Borgstahl

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Author profile →

4 papers

Recent·Most cited

Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition

J. Azadmanesh, K. Slobodnik, L. Struble, W. E. Lutz, L. Coates, K. L. Weiss, D. A. A. Myles, T. Kroll, G. E. Borgstahl

The paper investigates the mechanism of product inhibition in human MnSOD by combining neutron diffraction and X-ray absorption spectroscopy to determine the atomic and electronic structures of the enzyme in different states.

bioRxiv · Jan 26, 2024Biochemistry

Bacterial expression and purification of functional recombinant SARS-CoV-2 spike receptor binding domain

J. Prahlad, L. Struble, W. E. Lutz, S. A. Wallin, S. Khurana, A. Schnaubelt, M. J. Broadhurst, K. Bayles, G. E. O. Borgstahl

This paper describes a bacterial method to produce functional SARS-CoV-2 spike protein receptor binding domain for diagnostic and therapeutic applications.

bioRxiv · Feb 3, 2021 · PreprintBiochemistry

Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase

J. Azadmanesh, W. E. Lutz, L. Coates, K. L. Weiss, G. E. Borgstahl

This study uses neutron diffraction to directly observe proton and electron transfer mechanisms in MnSOD, revealing structural changes linked to redox states.

bioRxiv · Nov 2, 2020Biochemistry

Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells

S. Sagar, A. K. Rathinavel, W. E. Lutz, L. R. Struble, S. Khurana, A. T. Schnaubelt, N. K. Mishra, C. Guda, M. J. Broadhurst, S. P. Reid, K. W. Bayles, G. E. O. Borgstahl, P. Radhakrishnan

This study shows bromelain reduces ACE-2 and TMPRSS2 expression and inhibits SARS-CoV-2 infection in VeroE6 cells.

bioRxiv · Sep 16, 2020 · PreprintMicrobiology