Author

S. Sagar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Agrawal· 2 shared V. P. Singh· 2 shared A. Bremser· 1 shared A. Drougard· 1 shared A. Gheware· 1 shared A. K. Rathinavel· 1 shared A. P. Gheware· 1 shared A. T. Schnaubelt· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

A. Agrawal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An acute microglial metabolic response controls metabolism and improves memory

A. Drougard, E. H. Ma, V. Wegert, R. Sheldon, I. Panzeri, N. Vatsa, S. Apostle, L. Fagnocchi, J. Schaf, K. Gossens, J. Völker, S. Pang, A. Bremser, E. Dror, F. Giacona, , J. A. Pospisilik

The paper identifies an acute microglial metabolic response to high-fat diet that improves metabolism and memory by converting harmful fatty acids into beneficial metabolites.

bioRxiv · Apr 3, 2023Physiology

Obesity impairs therapeutic efficacy of mesenchymal stem cells by inhibiting cardiolipin-dependent mitophagy and intercellular mitochondrial transfer in mouse models of airway allergic inflammation

S. Sagar, M. I. Faizan, N. Chaudhary, A. Gheware, K. Sharma, I. Azmi, V. P. Singh, G. Kharya, U. Mabalirajan, A. Agrawal, T. Ahmad, S. S. Roy

This study shows that obesity impairs MSCs' ability to perform mitophagy and intercellular mitochondrial transfer, and that PQQ can restore these functions in obese-derived MSCs.

bioRxiv · Nov 27, 2021 · PreprintCell Biology

Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells

S. Sagar, A. K. Rathinavel, W. E. Lutz, L. R. Struble, S. Khurana, A. T. Schnaubelt, N. K. Mishra, C. Guda, M. J. Broadhurst, S. P. Reid, K. W. Bayles, G. E. O. Borgstahl, P. Radhakrishnan

This study shows bromelain reduces ACE-2 and TMPRSS2 expression and inhibits SARS-CoV-2 infection in VeroE6 cells.

bioRxiv · Sep 16, 2020 · PreprintMicrobiology

Adhatoda Vasica ameliorates cellular hypoxia dependent mitochondrial dysfunction in acute and severe asthmatic mice.

A. P. Gheware, L. Panda, K. Khanna, N. K. Bhatraju, V. Jain, S. Sagar, M. Kumar, V. P. Singh, S. Kannan, V. Subramanian, M. Mukerji, A. Agrawal, B. Prasher

This study shows Adhatoda Vasica extract reduces hypoxia-induced mitochondrial dysfunction and inflammation in asthma models, offering potential for treating severe steroid-resistant asthma.

bioRxiv · Apr 1, 2020 · PreprintImmunology