Black Dots: Microcontact-Printed, Reference-Free Traction Force Microscopy
K. M. Beussman, M. Y. Mollica, A. Leonard, J. Miles, J. Hocter, Z. Song, M. Stolla, S. J. Han, A. Emery, W. E. Thomas, N. J. Sniadecki
This paper introduces a traction force microscopy technique called 'black dots' to measure cellular forces without constraining cell shape, finding that higher force correlates with increased spread area, circularity, and F-actin uniformity in platelets.
bioRxiv · Aug 2, 2021Bioengineering