STAMP-Based Digital CRISPR-Cas13a (STAMP-dCRISPR) for Amplification-Free Quantification of HIV-1 Plasma Viral Load
R. Nouri, Y. Jiang, A. J. Politza, T. Liu, W. Greene, J. Nunez, X. L. Lian, W. Guan
This paper develops STAMP-dCRISPR, a digital CRISPR-Cas13a method for amplification-free HIV-1 viral load quantification, showing high accuracy and speed comparable to RT-qPCR.
bioRxiv · Oct 13, 2022 · PreprintBioengineering