Author

W. J. M. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

P. R. Patel· 4 shared N. Chen· 3 shared S. Ma· 3 shared Y. Li· 3 shared A. Zheng· 2 shared B. A. Yee· 2 shared B. S. Cho· 2 shared B. Zhou· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersImmunology

P. R. Patel

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 21, 2022

LncRNA Malat1 represses Th17 effector program by maintaining a critical bivalent super-enhancer and promotes intestinal inflammation

S. Ma, B. Zhou, Y. Abe…·W. J. M. Huang

This study shows that lncRNA Malat1 restricts Th17 cell IL-17A production by regulating a bivalent super-enhancer, thereby controlling intestinal inflammation resolution.

DOI 10.1101/2022.03.21.485192

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 14, 2021

RORγt serine 182 tightly regulates T cell heterogeneity to maintain mucosal homeostasis and restrict tissue inflammation

S. Ma, S. Patel, N. Chen…·W. J. M. Huang

This study shows that RORγt serine 182 regulates T cell heterogeneity in the intestine, maintaining homeostasis and limiting inflammation.

DOI 10.1101/2021.05.14.444071

mousescRNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 22, 2020

ADAR2 deaminase activity promotes Th17 effector function and protects against intestine inflammation

S. Ma, Y. Hao, B. S. Cho…·W. J. M. Huang

This study shows ADAR2 promotes Th17 effector function by editing Malt1, leading to increased IL-17A and protection against intestinal inflammation.

DOI 10.1101/2020.09.22.308221

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivMar 25, 2020

DDX5 targets tissue-specific RNAs to promote intestine tumorigenesis

N. Abbasi, T. Long, Y. Li…·W. J. M. Huang

This study identifies DDX5 as a regulator of tissue-specific oncogenic RNAs in intestinal tumorigenesis, showing its role in promoting colon and small intestine cancers.

DOI 10.26508/lsa.202000772

mouseexperimental assay

𝕏 PostBluesky