W. J. Song

Discovery of Highly Active Kynureninases for Cancer Immunotherapy through Protein Language Model

The paper identifies and validates four kynureninases using homology searches and protein language models, with the most active one showing significant tumor reduction in mouse models.

Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB

This study elucidates the molecular mechanism of substrate recognition by the macrocyclase PsnB in graspetide biosynthesis, revealing key interactions and structural features.