Author

Y.-H. Han

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

B. W. Warner· 1 shared C. Kim· 1 shared C. Seok· 1 shared E. J. Onufer· 1 shared G. J. Randolph· 1 shared G. M. Choi· 1 shared H. Eom· 1 shared H. J. Kim· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperImmunology

B. W. Warner

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Discovery of Highly Active Kynureninases for Cancer Immunotherapy through Protein Language Model

H. Eom, K. S. Cho, J. Lee, S. Kim, S. Park, H. Kim, J. Yang, Y.-H. Han, J. Lee, C. Seok, M. S. Lee, W. J. Song, M. Steinegger

The paper identifies and validates four kynureninases using homology searches and protein language models, with the most active one showing significant tumor reduction in mouse models.

bioRxiv · Jan 16, 2024Cancer Biology

Albumin-binding recombinant human IL-18BP ameliorates macrophage activation syndrome and atopic dermatitis via direct IL-18 inactivation

Y.-S. Jang, K. Lee, M. Park, J. J. Park, G. M. Choi, C. Kim, S. B. Dehkohneh, S. Chi, J. Han, M. Y. Song, Y.-H. Han, S.-H. Cha, S. G. Kang

This paper develops APB-R3, a long-acting IL-18 blocker, showing efficacy in reducing inflammation in macrophage activation syndrome and atopic dermatitis models.

bioRxiv · May 30, 2023Immunology

Intestinal epithelium-derived high density lipoprotein restrains liver injury via the portal vein

Y.-H. Han, E. J. Onufer, L. H. Huang, R. S. Czepielewski, B. W. Warner, G. J. Randolph

This study shows intestinal HDL neutralizes LPS in the portal vein, protecting the liver from injury in a mouse model of short bowel syndrome.

bioRxiv · Oct 1, 2020 · PreprintImmunology

Naringenin as an antibacterial reagent controlling of biofilm formation and fatty acid metabolism in MRSA

H.-S. Song, S. K. Bhatia, R. Gurav, T.-R. Choi, H. J. Kim, Y.-L. Park, Y.-H. Han, J. Y. Park, S. m. Lee, S. L. Park, H. S. Lee, W. Kim, Y.-G. Kim, Y.-H. Yang

This study identifies naringenin as an antibacterial agent that reduces biofilm formation and fatty acid secretion in MRSA and shows synergy with oxacillin.

bioRxiv · Mar 8, 2020 · PreprintMicrobiology