Author

W. K. Ray

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

R. F. Helm· 2 shared A. Pedraza· 1 shared B. Xu· 1 shared C. Tan· 1 shared D. Dougharty· 1 shared F. Henderson· 1 shared G. S. Bloom· 1 shared J. Li· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

R. F. Helm

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2 papers

Recent·Most cited

CADD from Chlamydia trachomatis is a manganese-dependent oxygenase that employs a self-sacrificing mechanism for the synthesis of p-aminobenzoate

R. Wooldridge, S. stone, A. Pedraza, W. K. Ray, R. F. Helm, K. D. Allen

This study characterizes CADD from Chlamydia trachomatis as a manganese-dependent oxygenase using self-sacrificing tyrosine and lysine residues for p-aminobenzoate synthesis.

bioRxiv · Aug 1, 2022 · PreprintBiochemistry

Human Tau Isoform Aggregation and Selective Detection of Misfolded Tau from Post-Mortem Alzheimer's Disease Brains

L. Wu, Z. Wang, S. Lad, D. Dougharty, S. Madhavan, M. Marcus, F. Henderson, W. K. Ray, C. Tan, S. Siedlak, J. Li, R. F. Helm, X. Zhu, G. S. Bloom, W. Zou, B. Xu

This study investigates human tau isoform aggregation in Alzheimer's disease, showing 3R tau aggregates faster than 4R and identifies key domains for aggregation, while demonstrating the use of RT-QuIC to detect misfolded tau.

bioRxiv · Dec 31, 2019 · PreprintPathology