Pharmacology & ToxicologybioRxiv
Computational drug repositioning of bortezomib to reverse metastatic effect of GALNT14 in lung cancer
O.-S. Kwon, H. Lee, H.-J. Kong…·H.-J. Cha
This study uses in silico drug repositioning to identify bortezomib as an inhibitor of GALNT14-driven lung cancer metastasis, validated through in vitro and in vivo experiments.
DOI 10.1038/s41388-020-1316-2