Saccharomyces cerevisiae as a platform for assessing sphingolipid kinase inhibitors
Y. Kharel, S. Agah, T. Huang, A. J. Mendelson, P. Barkey-Bircann, O. T. Eletu, J. Gesualdi, J. S. Smith, W. L. Santos, K. R. Lynch
The paper describes a high-throughput assay using Saccharomyces cerevisiae to assess sphingolipid kinase inhibitors and validates it with recombinant enzymes.
bioRxiv · Aug 17, 2017Biochemistry