Author

W. Lai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

L. Wu· 2 shared T. Wu· 2 shared Z. He· 2 shared D. Chen· 1 shared F. Yang· 1 shared H. Deng· 1 shared H. Guo· 1 shared J. Lv· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

L. Wu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Epigenetic regulation of alveolar macrophage homeostasis by histone deacetylase 1 and 2

W. Lai, M. Luo, Y. Wang, X. Li, Z. He, T. Wu, L. Wu

This study shows HDAC1 and HDAC2 are essential for alveolar macrophage homeostasis by suppressing Bim expression and co-regulating differentiation with LSD1.

bioRxiv · May 6, 2024 · PreprintImmunology

The Mechanism Insight into Bacterial Degradation of Pentachlorobiphenyl

L. Ji, X. Chang, L. Wang, X. Fu, W. Lai, L. Zheng, Q. Li, Y. Xing, Z. Yang, Y. Guan, F. Yang

This study identifies a new bacterium capable of degrading pentachlorobiphenyl and characterizes its enzymatic, proteomic, and metabolomic responses to the pollutant.

bioRxiv · Jan 18, 2024 · PreprintMicrobiology

Metabolic Nutrient Preferences of Vibrio mimicus: Leveraging Nucleotides and Oligopeptides from Yellow Catfish for Enhanced Infectivity

Y. Feng, J. Wang, W. Fan, Y. Geng, X. Huang, P. Ouyang, D. Chen, H. Guo, H. Deng, W. Lai, Z. Zuo, Z. Zhong

This study identifies host-specific metabolites that enhance Vibrio mimicus infectivity in yellow catfish by providing nutrients like deoxyguanosine.

bioRxiv · Jul 27, 2023 · PreprintMicrobiology

Regulation of pDC Fate Determination by Histone Deacetylase 3

Y. Zhang, Z. He, W. Lai, X. Shen, T. Wu, J. Lv, L. Wu

This study shows HDAC3 is essential for pDC development and hematopoietic progenitor homeostasis, with HDAC3 repressing cDC1-associated genes to promote pDC differentiation.

bioRxiv · Jun 8, 2022Immunology