Author

W. Nawaz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2

Frequent Co-Authors

B. Huang· 3 shared L. Zhu· 3 shared S. Xu· 3 shared X. Wu· 3 shared Z. Wu· 3 shared H. Shi· 2 shared L. Cheng· 2 shared Q. Hu· 2 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

B. Huang

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Author profile →

3 papers

Recent·Most cited

Short-term instantaneous prophylaxis and efficient treatment against SARS-CoV-2 in hACE2 mice conferred by an intranasal nanobody (Nb22)

X. Wu, Y. Wang, L. Cheng, F. Ni, L. Zhu, S. Ma, B. Huang, M. Ji, H. Hu, Y. Li, S. Xu, H. Shi, L. Liu, W. Nawaz, Q. Hu, , Z. Wu

This paper demonstrates that intranasal nanobody Nb22 provides short-term instantaneous prophylaxis and effective treatment against SARS-CoV-2 in hACE2 mice, with ultrahigh potency and long-lasting retention in the respiratory system.

bioRxiv · Sep 6, 2021Microbiology

AAV-Mediated In Vivo CAR Gene Therapy for Targeting Human T Cell Leukemia

W. Nawaz, B. Huang, S. Xu, Y. Li, L. Zhu, x. wu, Z. Wu

This paper describes an AAV-mediated in vivo CAR gene therapy that generates CAR T cells within the host, leading to tumor regression in a humanized mouse model.

bioRxiv · Feb 15, 2021Immunology

A potent bispecific nanobody protects hACE2 mice against SARS-CoV-2 infection via intranasal administration

X. Wu, L. Cheng, M. Fu, B. Huang, L. Zhu, S. Xu, H. Shi, D. Zhang, H. Yuan, W. Nawaz, P. Yang, Q. Hu, Y. Liu, Z. Wu

Nb15-NbH-Nb15, a bispecific nanobody with a heterotrimeric configuration, showed potent neutralization of SARS-CoV-2 in vitro and provided complete protection against infection in hACE2 mice via intranasal administration.

bioRxiv · Feb 8, 2021Microbiology