A network of mixed actin polarity in the leading edge of spreading cells
W.-L. Chung, M. Eibauer, W. Li, R. Boujemaa-Paterski, B. Geiger, O. Medalia
This study uses cryo-ET to reveal three distinct actin sub-domains in lamellipodia, including filaments with barbed ends pointing toward the cell center.
bioRxiv · Aug 26, 2022 · PreprintCell Biology