Adenosine Deaminase Acting on RNA 1 Associates with Orf Virus OV20.0 and Enhances Viral Replication
G.-R. Liao, Y.-Y. Tseng, J.-Y. Tseng, F.-Y. Lin, Y. Yamada, H.-P. Liu, C.-Y. Kuan, W.-L. Hsu
This study identifies a novel interaction between ORFV protein OV20.0 and ADAR1, showing OV20.0 suppresses ADAR1's A-to-I editing and enhances viral replication by inhibiting PKR phosphorylation.
bioRxiv · Nov 1, 2018Microbiology