Author

Wei Gu

Nanjing Normal University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:deconvolution· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Brian D O'Donovan· 1 shared Chen ZhouiD· 1 shared Emily D Crawford· 1 shared Eric D Chow· 1 shared Hanna Retallack· 1 shared Jing Yun PengiD· 1 shared Joseph L DeRisi· 1 shared Lin LiiD· 1 shared

Activity by Year

2015-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperGenomics

Brian D O'Donovan

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3 papers

Recent·Most cited

HSC71 acetylation confers protection against Spiroplasma eriocheiris infection by inhibiting apoptosis and promoting ROS production in arthropods

Yubo Ma, Xiang Meng, Xin Yin, Yao Yu, Shuai Lü, Wei Gu, Qingguo Meng

This study shows that acetylation of HSC71 by Crat protects arthropods from Spiroplasma eriocheiris infection by reducing apoptosis and increasing ROS production.

bioRxiv · Mar 4, 2026 · PreprintImmunology

Cytokine-driven cellular polarization in preeclampsia revealed through the "Dictionary of immune responses"

Sheng Biao Wan, Tianfan Zhou, Yingxuan Ma, Ying Chen, Chen Zhou, Jing Yun Peng, Lin Li, Weijia Luo, Wei Gu, Zhiwei Liu, Xiaolin Hua

The paper identifies cytokine-driven cellular polarization in preeclampsia using single-cell sequencing and machine learning, revealing altered immune cell states and potential therapeutic targets.

bioRxiv · Mar 26, 2025 · PreprintBioinformatics

Depletion of Abundant Sequences by Hybridization (DASH): Using Cas9 to remove unwanted high-abundance species in sequencing libraries and molecular counting applications

Wei Gu, Emily D Crawford, Brian D O'Donovan, Michael R Wilson, Eric D Chow, Hanna Retallack, Joseph L DeRisi

DASH uses Cas9 to deplete high-abundance sequences in sequencing libraries, improving detection of low-abundance targets in various applications.

bioRxiv · Nov 20, 2015Genomics