Author

Weiyi Guo

Georgetown University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Andrew Hoy· 1 shared Anqi Feng· 1 shared Arun KrishnarajiD· 1 shared Aykut ÜreniD· 1 shared Cong Rong· 1 shared Douglas KungiD· 1 shared Guantao Zheng· 1 shared Guodong CheniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Andrew Hoy

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2 papers

Recent·Most cited

Transcriptome-wide mapping reveals a non-canonical RNA-dependent mechanism of platinum cancer drugs

Arun Krishnaraj, Xinrui Wei, Richi Thakral, Weiyi Guo, Siva Bala Subramaniyan, Xiaopei Zhang, Katelyn R. Alley, Anqi Feng, Andrew Hoy, Douglas Kung, Purushottam Babu Tiwari, Aykut Üren, Rodrigo A. Maillard, Victoria J. DeRose, Sreejith J. Nair

The paper identifies cisplatin as an RNA binder and shows its cytotoxicity is partially mediated through RNA binding, revealing a noncanonical mechanism of action.

bioRxiv · Sep 16, 2026 · PreprintMolecular Biology

MobiChIP: a compatible library construction method of single-cell ChIP-seq based droplets

Xianhong Yu, Guantao Zheng, Liting Xu, Weiyi Guo, Guodong Chen, Yiling Zhu, Tingting Li, Mingming Rao, Linyan Wang, Cong Rong, Hao Pei

MobiChIP enables high-throughput single-cell ChIP-seq using droplets, integrating with scRNA-seq to reveal epigenetic and genetic heterogeneity in PBMCs.

Molecular Omics · Oct 17, 2024Peer-reviewedMolecular Biology