Molecular BiologybioRxivPreprint
Transcriptome-wide mapping reveals a non-canonical RNA-dependent mechanism of platinum cancer drugs
Arun Krishnaraj, Xinrui Wei, Richi Thakral…·Sreejith J. Nair
The paper identifies cisplatin as an RNA binder and shows its cytotoxicity is partially mediated through RNA binding, revealing a noncanonical mechanism of action.
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