Author

Andrew Hoy

Georgetown University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Rodrigo A. MaillardiD· 2 shared Anqi Feng· 1 shared Anwar Dakwar· 1 shared Arun KrishnarajiD· 1 shared Aykut ÜreniD· 1 shared Daniela BertinettiiD· 1 shared Douglas KungiD· 1 shared Friedrich W. HerbergiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Rodrigo A. MaillardORCID

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2 papers

Recent·Most cited

Transcriptome-wide mapping reveals a non-canonical RNA-dependent mechanism of platinum cancer drugs

Arun Krishnaraj, Xinrui Wei, Richi Thakral, Weiyi Guo, Siva Bala Subramaniyan, Xiaopei Zhang, Katelyn R. Alley, Anqi Feng, Andrew Hoy, Douglas Kung, Purushottam Babu Tiwari, Aykut Üren, Rodrigo A. Maillard, Victoria J. DeRose, Sreejith J. Nair

The paper identifies cisplatin as an RNA binder and shows its cytotoxicity is partially mediated through RNA binding, revealing a noncanonical mechanism of action.

bioRxiv · Sep 16, 2026 · PreprintMolecular Biology

Allosteric modulation of protein kinase A in individuals affected by NLPD-PKA , a neurodegenerative disease in which the RIβ-L50R variant is expressed

Tal Benjamin‐Zukerman, Valeria Pane, Rania Safadi‐Safa, Meir Solomon, Varda Lev‐Ram, Mohammad Aboraya, Anwar Dakwar, Daniela Bertinetti, Andrew Hoy, Merel O. Mol, John Cornelis Van Swieten, Rodrigo A. Maillard, Friedrich W. Herberg, Ronit Ilouz

This study investigates the RIβ-L50R variant in NLPD-PKA, showing it causes misfolding, disrupts PKA holoenzyme assembly, and increases C-subunit nuclear translocation, with a potential therapeutic strategy to reduce dissociation.

FEBS Journal · Apr 17, 2025Peer-reviewedCell Biology